[8] The main objective of the game is to collect a piece of cheese placed in at least one location on a map.

Dying adds one point to a player's score on the scoreboard, no matter what time in the game it is or the cause of death.

The general objective of the Shaman is to help the other mice obtain the cheese and bring it back to the hole.

Doing so will award the Shaman with "saves" for each mouse who completes the map, which are recorded onto the player's profile.

The Shaman can do so by summoning objects such as planks, boxes, anvils, spirit, and balloons to create buildings or contraptions such as bridges to cross gaps or various other obstacles.

In lieu of this, hard mode Shamans can create a pre-made 'totem', which is constructed on an in-game editor map.

Players can also buy virtual clothing items by purchasing 'fraises', an in-game currency that can be obtained by paying real money.

Titles are awarded for collecting specific numbers of cheese, obtaining a certain amount of first place victories, accumulating saves as a Shaman, buying items from the shop and completing events.

Badges are awarded for buying any type of fur (except plains) from the shop and completing events.

The abilities are separated into five trees: Spiritual Guide, Wind Master, Mechanician, Wildling, and Physicist.

Normal mice can troll by stalling, which is to stay on the map for as long as possible without capturing the cheese.

Trollers can also use the in-game consumables to make a shaman build go haywire or slow down mice.

Before Transformice, Tigrounette had worked on another online flash game in April 2008 titled Aaaah!.

The object of the game was to control a stick figure-like character through a silhouetted map to reach a pharmacy.