[9] Five years on and A$354 million in funding from the Australian and Queensland Governments, UQ and QUT, TRI became operational and four institutes came together.

TRI was established in January 2013 and officially opened in October of the same year by the Governor-General Dame Quentin Bryce.

[10] Over 800 researchers and clinicians from TRI’s four shareholders undertake medical research and clinical studies into cancer; inflammation and infection; obesity and diabetes; kidney disease and liver disease; and bone and joint disorders.

[14] The facility features eight levels: four levels of laboratories, administration and teaching facilities, an auditorium and conference rooms, staff amenities and an "outdoor room" atrium area.

It stands on the grounds of the Princess Alexandra Hospital in Brisbane on the former site of the Vision Australia building, of which the red clay bricks were salvaged and reused as the base of TRI.