The series centres on Bashir "Bash" Hamed, a doctor from Syria who comes to Canada as a refugee during the Syrian Civil War,[a] and is rebuilding his career as a medical resident in the emergency department at the fictional York Memorial Hospital in Toronto.

[12] Transplant follows Dr. Bashir "Bash" Hamed, a Syrian Civil War refugee and the newest resident at York Memorial Hospital, as he navigates through numerous obstacles to resume a career in the high stakes world of emergency medicine.

[47][48] In July 2023, NBC originally announced season 3 would premiere on October 5, 2023, moving to Thursdays at 9 p.m. to fill the timeslot of Law & Order: Special Victims Unit.

However, on August 28, it was announced that NBC pushed back the premiere date to October 12, delayed by a week as part of schedule changes for the fall lineup.

[53] In November 2020, Sky Witness acquired the UK rights to the drama after striking a deal with international distributor NBC Universal Global Distribution.

He praised the series and Haq's lead performance in particular, ultimately concluding that "There are numerous medical dramas that move with a breathless, hectic pace and then stop for some romance or heart-warming moments.

[60] The Hollywood Reporter observed that it was "not a hugely innovative or adventurous medical drama" and had a "heavy reliance on that House trope of a loved one bringing in a patient, only to have the loved one be the one with the actual medical mystery", but that Hamed was "an interesting main character" and Haq was a "solid leading man, giving Bashir a frazzled soulfulness, but never making him saintly".

In conclusion, it was felt that "in a fall in which the broadcast drama slate is populated mostly by mediocre acquisitions and dismal holdovers from last midseason, there's value to an above average new show like Transplant.