Tre'Quan Smith (born January 7, 1996) is an American professional football wide receiver.

[8] On January 6, 2018, Smith released a statement through his Twitter account announcing his decision to forgo his remaining eligibility and declare for the 2018 NFL Draft.

[10] Smith had a solid week of practice during the Senior Bowl and was able to maintain his draft stock.

On January 27, 2018, Smith caught five receptions for 83 yards and scored on a 14-yard touchdown pass by quarterback Mike White to help the North defeat the South 45–16.

[12] On March 29, 2018, he participated in Central Florida's pro day, but opted to stand on his combined numbers and only performed positional drills.

[13][14] After the pre-draft process, Smith was projected to be a third or fourth round pick by NFL draft experts and scouts.

During a 48–7 Week 11 victory over the reigning Super Bowl champion Philadelphia Eagles, he recorded ten receptions for 152 yards and a touchdown.

The Saints finished with the top seed in the NFC with a 13–3 record and received a first-round postseason bye.

[26] In the 2019 season-opener against the Houston Texans, Smith caught two passes for 26 yards and a touchdown in the narrow 30–28 victory.

[32] On January 16, 2021, Smith was activated off of the injured reserve ahead of the Saints' Divisional Round game against the Buccaneers.