The following GSM and CDMA2000 mobile phone operators currently or previously offered a custom-branded (OEM) version of the Treo 650: In release order As seen on Palm's support page,[4] these carriers are the sole providers of support for the OEM phones.

At the time of its release, a significant number of users experienced problems with Palm's new Non-Volatile File System, or NVFS, based on the FAT filesystem.

[5] To remedy the initial complaints, Palm offered a free 128 MB SD flash card to Treo 650 users.

Other main concerns surrounding the Treo 650 (during its initial release period) were as follows: On March 22, 2005, palmOne released the first ROM/Firmware Update Archived 2005-04-29 at the Wayback Machine (v1.12) for Sprint-branded phones which alleviated the NVFS inefficiency, random resets and the microphone problems.

The Rogers Wireless Treo 650 Firmware Update was quietly posted at the Rogers Wireless Treo 650 support site, and like the Unlocked GSM Firmware Update, fixes the main concerns during the initial release period.

The second was named the "Black tie" limited edition[7] targeting the Asia/Pacific region, released in 2006 and limited to 2000 units, an all black Silicone coated device celebrating 10 years of Palm, these also carried the "Palm" as opposed to the "PalmOne" logo.