After Big Eyes, Small Mouth, Guardians of Order would go on to achieve significant success with The Sailor Moon Role-Playing Game and Resource Book.

Guardians of Order acquired licenses and published Big Eyes, Small Mouth-based RPGs for a number of other anime series including Dominion, Demon City Shinjuku, and Tenchi Muyo!.

After El Hazard, the last such game, the company's strategy with licensed anime series changed and it began issuing "Ultimate Fan Guides" which served the same purpose while avoiding the need to reprint the same BESM-based mechanics.

Mark C. MacKinnon created the company Guardians of Order to publish his anime game, Big Eyes, Small Mouth (1997).

In 2002, Guardians of Order launched their "Magnum Opus" program, licensing the company's intellectual property to third parties to create new games.

The announcement stated the company was "extremely confident" that a release date of January 2007 would be met and confirmed that those who pre-ordered and prepaid for the book would be "in good hands," though it was also said that they have not taken on Guardians of Order's liabilities.

[6] On March 7, 2007 George R. R. Martin wrote that he had regained control of his intellectual property rights and was "all square" with Guardians of Order.