Now primarily used for administrative purposes, several plans have been proposed to reuse the site, or to preserve the building as a historic landmark.

[2][3][7][8] It is located at the top of a hill,[5]: 5, 15  part of the terminal moraine that runs west-to-east across Long Island.

New York City Commissioner of Hospitals Dr. Sigismund Goldwater and Department of Public Works architect Isadore Rosenfield supervised the design.

[5][12][14] The building was sited at an angle to the north–south grid, with its main entrance facing southwest towards the intersection of Parsons and 82nd Drive.

[7][8][12] It was designed with numerous windows and glass interior walls, glass-enclosed sunrooms or solariums, and cantilever balconies, all to maximize natural light entering the facility and exposure of patients to the sun.

[7][11][12] Its basement was built with locker, dining, and storage facilities, along with a tunnel connecting to the then-Queens General Hospital buildings.

[5][17] Triboro Hospital's outer design has a "symmetrical facade and a minimum of ornamentation," utilizing gray brick and limestone trim.

[18][19] The T Building is currently used by Queens Hospital Center for administrative offices, storage, and clinic and psychiatric services.

[25][31][32] In 1936, the city planned to construct a new tuberculosis hospital adjacent to Queens General and Queensboro Pavilion, pending funding.

[5]: 20 [36][37] Groundbreaking on Triboro Hospital took place on August 3, 1938, attended by Mayor Fiorello H. La Guardia.

"[44][49] During the various ceremonies, Mayor La Guardia expressed regret for the conditions that ultimately led to the high prevalence of tuberculosis within New York City, making Triboro Hospital necessary.

La Guardia attributed the high rates of the disease to a lack of high-quality housing, and the city not keeping up with modern medicine.

La Guardia claimed that slum clearance and improved housing programs would eliminate the disease and the need for institutions like Triboro Hospital.

[25][52] In spite of the unification, Queens General and Triboro Hospital continued to operate largely independent of each other.

Patients from QHC and Elmhurst Hospital Center would receive preference in applying for housing in the complex.

[82][83] In January 2014, Queens Community Board 8 (representing Hillcrest) voted to demolish the former Triboro Hospital, in part due to its condition and maintenance costs, but also to prevent the housing plan from moving forward.

[85][86][87] In January 2018, the New York City Council approved plans to renovate Triboro Hospital for use as affordable housing, with 206 units provided in the building.

The remaining 75 would be for individuals who make less than 60 percent of the Area Median Income (AMI), including people who were formerly homeless.

[90] In June 2018, Triboro Hospital was nominated as a potential landmark on the National Register of Historic Places by New York State.