Throughout the company's existence, Tribune Entertainment mainly produced first-run syndicated programs (including Geraldo, At the Movies and Earth: Final Conflict), along with some television special (such as the Hollywood Christmas Parade and Soul Train Music Awards).

In 1982, Tribune picked up newspaper film critics Roger Ebert and Gene Siskel under the show name of At the Movies before losing the hosts four years later to Buena Vista Television.

[17] In January 1994, Tribune Entertainment started a country music initiative across broadcast television, concert touring, direct marketing, home video distribution, pay-per-view and radio syndication.

[19] In July 1995, Tribune sold 22 episodes of "Road", their canceled country music show, to The Nashville Network for broadcast starting in January 1996.

[20] In 1996, it entered into an agreement with King World Productions to distribute Geraldo, which would remain on the air until 1998 via a joint first-run development pact deal, and Tribune to continue handling barter advertising sales of the show.

[22] In July 2003, the company purchased syndication rights to 34 DreamWorks Pictures feature films to use on Tribune stations starting in August 2006.

Tribune Studios will produce programs primarily for the company's 23 television stations and WGN America, some of which will receive national distribution.

[27] Tribune Studios's first original drama, since its formation,[28][29] for its sister company WGN America was Manhattan which aired from 2014 to 2015 for 2 seasons.