It issues minute branches to the tentorium cerebelli, and the dura mater in the middle cranial fossa.

[citation needed] Medially to the trigeminal ganglion are the internal carotid artery, and the posterior part of the cavernous sinus.

[2] The greater petrosal nerve passes underneath the trigeminal ganglion to reach the foramen lacerum.

[3]: 498, 509 After recovery from a primary herpes infection, the virus is not cleared from the body, but rather lies dormant in a non-replicating state within the trigeminal ganglion.

[citation needed] In rodents, the trigeminal ganglion is important as it is the first part of the pathway from the whiskers to the brain.