The Santander blind snake (Trilepida nicefori) is a species of snake in the family Leptotyphlopidae.

The specific name, nicefori, is in honor of missionary Brother Nicéforo María (1888–1980), born Antoine Rouhaire in France, who established a natural history museum in Medellin, Colombia.

[5] T. nicefori is known only from Santander Department, Colombia.

Adults may attain a total length (including tail) of 10.5 cm (4.1 in).

It is uniform brown dorsally, and beige ventrally.