Trimble is a town in Dyer and Obion counties in the U.S. state of Tennessee.

[7] The Dyer County portion of Trimble is part of the Dyersburg, TN Micropolitan Statistical Area, while the Obion County portion is part of the Union City, TN–KY Micropolitan Statistical Area.

The town was first settled in 1873 on land owned by local Jesse Pierce.

[8] The following year, the town was named Trimble Station, when the Paducah & Memphis Railroad extended its line from Troy Station, TN south to the Dyer County line.

[11] According to the United States Census Bureau, the town has a total area of 0.6 square mile (1.7 km2), all land.

28.0% of all households were made up of individuals, and 14.7% had someone living alone who was 65 years of age or older.