It is part of the 17th century Trinitatis Complex, which includes the Rundetårn astronomical observatory tower and the Copenhagen University Library, in addition to the church.

Built in the time of Christian IV, the church initially served the students of Copenhagen University.

[2] There were three builders, namely Hans van Steenwinckel the Younger, Leonhard Blasius, and Albertus Mathiesen.

The roof structure was ignited, a spire crashed into the library, punching a hole in some of the arches of the church.

The furnishings were renewed with an altarpiece and pulpit by Friederich Ehbisch (1731) and a large Baroque clock (1757).

The Trinitatis Complex was hit during the 1807 British bombardment of Copenhagen, and damaged by major fires.

The small shops on the corner of Landemærket were closed, as was the remainder of the cemetery north of the church.

A major restoration was completed in 1834-35 by Gustav Friedrich Hetsch, funded by a bequest from Christopher Hauschildt.

Most of the work took place inside the building, including a vestry, detached on the south side of the choir.

External renovations occurred 1869-71 by a design of Niels Sigfred Nebelong in connection with a change in the church's patronage.

The brickwork was laid in a cross-linking pattern of yellow and red stripes, obscured by accumulated dirt.

The sanctuary was divided by two rows of seven columns in the longitudinal direction matching the church's exterior.

What once functioned as the Library Hall now serves as an exhibition gallery and venue for classical concerts.

Positioned on the south side of the church, features include a burial vault (1870) and granite tiles (1928-29).