In March 1965, a second referendum was passed approving the purchase of an 86 acres (34.8 ha) campus site at Fifth Avenue and Palmer Street in River Grove.

Triton College opened in September 1965 and held classes at several of the high schools in its district.

With the opening of the Learning Resource Center in 1974, the original campus plan was essentially complete, except for some athletic facilities and the Performing Arts Center, a large auditorium planned for the area now occupied by the soccer field, but never built.

By 1975, enrollment had grown to nearly 20,000, in-district tuition had increased to US$11 per semester hour, and Triton had become the largest single-campus community college in Illinois.

The college also offers the academically rigorous Scholars Program for high achieving incoming freshman.

[7] Students also participate in the Tritonysia play festival, write and edit the Fifth Avenue Journal, and other artistic endeavors.

Triton competes in NJCAA and is a member of the North Central Community College Conference (N4C).