Trofeo Alfredo Binda-Comune di Cittiglio is a women's professional road bicycle racing event held annually in the comune (municipality) of Cittiglio and nearby comunes located within the Province of Varese in the region of Lombardy in northern Italy.

[1] From 2025, the race has moved backwards one week in the calendar, allowing Milano–San Remo Donne to join the UCI Women's World Tour.

Trofeo Alfredo Binda is held in the Province of Varese in the region of Lombardy in northern Italy.

[10] The circuit passes through Brenta, Casalzuigno, Casale Alto, Cuveglio, Cuvio, Azzio, Gemonio before returning to Cittiglio.

Other climbs that have featured on the route include the Masciago Primo (5.1km at 4.6%), Caldana (2.2km at 4.5%) and Cunardo (4km at 4.8%).