It opened on 5 August 1864,[1] ten years after the Trunk Line between Oslo and Eidsvoll Municipality opened.

The 49 kilometer long (later 51.1 km) railway line was narrow gauged (1,067 mm (3 ft 6 in)) and went between the city of Trondheim and the village of Støren (in what is now Midtre Gauldal Municipality in Trøndelag county, Norway).

[1] The railway had its station, Trondhjem Kalvskinnet Station, in Prinsens gate, crossed the Nidelva river on a newly constructed railroad bridge to Elgeseter, the Elgeseter Bridge.

In 1884 the railway tracks were relocated to the west side of the Nidelva and joined with the Meråker Line and the new railway station at Brattøra, which had opened in 1882.

In 1921 the railway was converted to standard gauge and became a part of the Dovre Line.