She was the author of 12 books, including Judaism and Christianity: The differences (1943), Toward Jewish-Muslim Dialogue (1967), and Freedom and Jewish Women (1977).

Weiss-Rosmarin and her husband opened the School of the Jewish Woman in Manhattan in October 1933 under the auspices of Hadassah, the Women's Zionist Organization of America.

The school, which closed in 1939, was modeled on the Frankfurt Lehrhaus created by Franz Rosenzweig and Martin Buber, and aimed to combat what Weiss-Rosmarin saw as women's poor access to education.

Out of the school's newsletter grew the Jewish Spectator, which described itself as a "typical family magazine with a special appeal to women."

[1][2] Weiss-Rosmarin also wrote a regular column, "Letters from New York", in the London Jewish Chronicle and served as national co-chair of education for the Zionist Organization of America.