Truth serum

"Truth serum" is a colloquial name for any of a range of psychoactive drugs used in an effort to obtain information from subjects who are unable or unwilling to provide it otherwise.

Reliability and suggestibility of patients are concerns, and the practice of chemically inducing an involuntary mental state is now widely considered to be a form of torture.

[9][10] Sedatives or hypnotics that alter higher cognitive function include ethanol, scopolamine, 3-quinuclidinyl benzilate, potent short or intermediate acting hypnotic benzodiazepines such as midazolam, flunitrazepam, and various short and ultra-short acting barbiturates, including sodium thiopental (commonly known by the brand name Pentothal) and amobarbital (formerly known as sodium amytal).

The judge stated: "We are of the considered opinion that no individual can be forced and subjected to such techniques involuntarily, and by doing so it amounts to unwarranted intrusion of personal liberty.

He had noted that women in childbirth who were given scopolamine could answer questions accurately even while in a state of twilight sleep, and were oftentimes "exceedingly candid" in their remarks.

[12][2] The United States Office of Strategic Services (OSS) experimented with the use of mescaline, scopolamine, and marijuana as possible truth drugs during World War II.

The barbiturates, by disrupting defensive patterns, may sometimes be helpful in interrogation, but even under the best conditions they will elicit an output contaminated by deception, fantasy, garbled speech, etc.

[16]In 1963, the U.S. Supreme Court ruled, in Townsend v. Sain, that confessions produced as a result of ingestion of truth serum were "unconstitutionally coerced" and therefore inadmissible.

[35] The viability of forensic evidence produced from truth sera has been addressed in lower courts – judges and expert witnesses have generally agreed that they are not reliable for lie detection.

[36] In 1967, during his investigation into the assassination of President John F. Kennedy, New Orleans District Attorney Jim Garrison arranged for his key witness, Perry Russo, to be administered sodium pentothal before being questioned about his knowledge regarding an alleged conspiracy.

More recently, a judge approved the use of narcoanalysis in the 2012 Aurora, Colorado shooting trial to evaluate whether James Eagan Holmes's state of mind was valid for an insanity plea.

[39] Judge William Sylvester ruled that prosecutors would be allowed to interrogate Holmes "under the influence of a medical drug designed to loosen him up and get him to talk", such as sodium amytal, if he filed an insanity plea.

"[40] Psychology Today's Scott Linfield noted, as per Piper, that "there's good reason to believe that truth serums merely lower the threshold for reporting virtually all information, both true and false.

Sodium thiopental , marketed as Pentothal
Amobarbital , one of the chemical compounds that can be used as a truth serum