These are:[2][3][4] Tsotne Dadiani's career unfolded against the background of decline of Georgia as a major regional power in the face of the Khwarazmian and Mongol invasions.

Around 1228, Tsotne was among the commanders of a large army summoned by Queen Regnant Rusudan to free Georgia from the Khwarazmian troops of Jalal ad-Din Mingburnu.

During this period of interregnum (1245–1250), with the two Davids absent at the court of the Great Khan in Karakorum, the Mongols divided the Kingdom of Georgia into eight districts (tumen), each governed by a leading Georgian noble.

[7] Around 1246,[8] Tsotne Dadiani joined other Georgian nobles in a clandestine meeting at the castle of Kokhtastavi, in Javakheti, to discuss an overthrow of the Mongol overlordship.

The arrested Georgian dignitaries, on being brought to Shirakavan before the noyan Chormaqan, insisted that they had no intention of rebelling, but had merely met to arrange the levying of the kharaj, or tribute to be paid to the Mongols.

On 26 October 1999, he was canonized by the Holy Synod of the Georgian Orthodox Church as Saint Tsotne Dadiani the Confessor, instituting his feast day on 30 July.