The station consists of a single island platform situated underground.
[1] Tsukuba Center bus terminal existed prior to the railway station opening.
[2] The station is located at the heart of the "science city" of Tsukuba.
Now, there is also a commercial complex named BiVi Tsukuba (ビビつくば)[4] next to the bus terminal.
The commercial complex has an information desk operated by Kantō Railway, where tickets can be purchased.