[6] Eusebius mentioned Thebez being 13 Roman miles east of Neapolis (Nablus), which led to it being identified with Tubas, which is 16 km (10 mi.)

[7] In the late 19th century, with Palestine still being Ottoman rule, groups of Arabs belonging to the Daraghmeh clan—mostly shepherds and farmers who lived in the Jordan Valley—migrated northward to the site because of its fertile ground, proximity to several springs, and its high elevation compared to the Jordan Valley and Wadi al-Far'a plain;[6] Mount Gerizim was visible from the area.

[8] The Daraghmeh clan had lived in the Jordan Valley since the 15th century and in addition to Tubas, they founded or inhabited the nearby hamlets of Kardala, al-Farisiya, Khirbet al-Malih, Kishda, Yarza, and Ras al-Far'a.

Soon after being established in Tubas, Arabs from Najd, Syria, Transjordan, Hebron and nearby Nablus came to settle in the area.

[6] During this period, Tubas became the site of clashes between the 'Abd al-Hadi and Tuqan families of Nablus and suffered incursions by Bedouins from areas east of the city.

Most of the inhabitants resided in mud-built houses or tents in order to work on their distant lands in the Jordan Valley and to graze their sheep and goat flocks.

[10] According to traveler Herbert Rix, compared to other towns of its size in Samaria, Tubas was "well-to-do" and had abundant amounts of timber, which was harvested for firewood.

Livestock products included cheese, clarified butter, woolen rugs, tents, ropes, and cloth bags.

[12] In 1877, Lieutenant Kitchener of the Palestine Exploration Fund (PEF) survey team, reported uncovering an Arabic inscription buried in the wall of the village mosque recording its building and dedication.

He also wrote that the villagers had paid a bribe of £100 in gold to the Pasha of Nablus to avoid their young men being conscripted into the Turkish army fighting in Crimea.

[13] The PEF noted that the Samaritans believed that the tomb of Asher, known locally as Nabi Tota ("the good prophet"), was located in Tubas.

Tubas was transferred to Palestinian National Authority (PNA) control in 1995 under the Interim Agreement on the West Bank and the Gaza Strip.

[25] Tubas has not seen as much violence in the Israeli–Palestinian conflict as nearby Nablus and Jenin, but a number of incidents occurred during the Second Intifada, which began in 2000.

[26][27] On August 31, 2002, an Israeli Apache helicopter fired four Hellfire missiles at a civilian car suspected of carrying a local al-Aqsa Martyrs Brigades commander and a nearby home.

The strike instead killed five civilians, including two children, two teenagers and a 29-year-old Fatah activist accused of being a member of the al-Aqsa Brigades.

The Israeli Defense Minister, Binyamin Ben-Eliezer, issued a statement expressing "regret" over "harming" civilians in Tubas.

[29] On 27 August 2024, the IDF invaded Tubas along with Nablus, Jenin and Tulkarm as part of their "Summer Camp" offensive.

[6] In a 1945 land survey, Tubas along with nearby Bardala and Kardala consisted of 313,123 dunams (31,312 hectares) of which 220,594 was Arab-owned and the remainder being public property.

[19] As of 2005[update], its total land area consists of 295,123 dunams (29,512 hectares), of which 2,271 is classified as built-up, roughly 150,000 used for agricultural purposes and about 180,000 has been expropriated by Israel for military bases and buffer zone.

[6] About 1,100 residents fled Tubas after the 1967 Six-Day War mostly to the Souf refugee camp in Jordan,[31] while 260 immigrated there and in 1981 its population was 5,300.

[37] The inhabitants of Tubas are predominantly Muslims,[2][8] but there is a community of approximately 60 Palestinian Christians, all belonging to the Greek Orthodox Church.

A major factor that has resulted from the conflict was the confiscation of agricultural land located within the city's or its governorate's jurisdiction by Israeli settlements or military authorities.

[39] Currently, agriculture constitutes 60% of Tubas' economic activity, public services comprise 17%, trade is 10%, Israeli labor is 8%, construction and industry make-up the remaining 5%.

Israeli trenches around the neighboring villages of Ras al-Ahmar and Khirbet al-'Atuf prevent access to nearly 40% of Tubas' arable lands.

The factory specializes in the production of Italian cheese and primarily targets cosmopolitan consumers in Ramallah, Bethlehem and Jerusalem as well as international workers and diplomats living in the West Bank.

Since 1995, Tubas has been located in Area A, giving the PNA full control over its security, administration and civilian affairs.

[6] Tubas has been governed by a municipal council since 1953, when it was granted permission to do so by Jordanian authorities who controlled the West Bank at the time.

It is collected 3-4 times daily from the residential area, which is sent to a shared dumping site 3 kilometers (1.9 mi) from the city.

Tubas is not connected to the sewage network, therefore all households dispose of their waste water in cesspits, a major source of pollution in groundwater.