[1] He later began a successful career as session drummer, playing with many international artists, including Gerry Mulligan, Chet Baker, Stéphane Grappelli, Massimo Urbani, Gil Evans, Slide Hampton, Don Costa, Tony Scott, Ástor Piazzolla, Aldemaro Romero, Gato Barbieri, Eumir Deodato, Mina, Lucio Dalla, Franco Battiato, Fabrizio De André, Pino Daniele, Manu Chao and others.

Between the 1970s and 1980s, De Piscopo played on several occasions with bassist-arranger Pino Presti, with whom he established one of the top rhythm sessions in the Italian music scene.

[2][3][4][5][6][7][8][9][10][11] In 1979 De Piscopo played the drums in the album L'era del cinghiale bianco by the singer-songwriter Franco Battiato.

[12] His 1985 song "Radio Africa" (written by Lino Nicolosi and Dora Carofiglio) was a collaboration with Guinean singer Mory Kanté.

Current DragonForce drummer Gee Anzalone was taught by Piscopo at the NAMM Academy in Milan and refers to him as an influence.