The Gnome-Rhône 14K Mistral Major was a 14-cylinder, two-row, air-cooled radial engine.

It was Gnome-Rhône's major aircraft engine prior to World War II, and matured into a highly sought-after design that would see licensed production throughout Europe and Japan.

Thousands of Mistral Major engines were produced, used on a wide variety of aircraft.

Starting in 1926, however, they used the basic design of the Titan to produce a family of new single-row radial engines, the so-called "K series".

Among the licensees were Industria Aeronautică Română in Romania, Manfred Weiss in Hungary, Alvis of the UK, Tumansky in the USSR, Walter of Czechoslovakia, and Isotta Fraschini and Piaggio in Italy.