The Tumuk Humak Mountains (Dutch: Toemoek-Hoemakgebergte, Portuguese: Serra do Tumucumaque, French: Monts Tumuc Humac) are a mountain range in South America, stretching about 120 kilometers (75 mi) east–west in the border area between Brazil in the south and Suriname and French Guiana in the north.

In the language of the Apalam and Wayana peoples, Tumucumaque means "the mountain rock symbolizing the struggle between the shaman and the spirits".

The Tumuk Humak Mountains are part of the Tumucumaque Uplands of the Guiana Shield.

They are geographically important because they form the divide between the biogeographical system of the Amazon Basin and that of the Atlantic coastal area of the Guianas.

[2] The French film Tumuc Humac (1970), directed by Jean-Marie Périer, was named after the mountain range.