Tupelo is a town in Jackson County, Arkansas, United States.

[3] According to the United States Census Bureau, the town has a total area of 0.31 square miles (0.8 km2), all land.

As of the census[5] of 2000, there were 177 people, 76 households, and 50 families residing in the town.

27.6% of all households were made up of individuals, and 15.8% had someone living alone who was 65 years of age or older.

About 13.3% of families and 23.4% of the population were below the poverty line, including 26.1% of those under the age of 18 and 25.0% of those 65 or over.