Tupua Tamasese Meaʻole CBE (3 June 1905 – 5 April 1963) was a Western Samoan paramount chief.

He was born in Vaimoso in 1905, one of three sons of the paramount chief Tupua Tamasese Lealofi I.

[1] In 1929, he was installed as Tupua Tamasese when his elder brother and Mau leader, Tupua Tamasese Lealofi III was assassinated by colonial police during a Mau parade in Apia.

[1] Away from politics, Tamasese was involved in business, serving as chair of the board of the Western Samoa Trust Estates Corporation, a director of the Bank of Western Samoa and a member of the Copra Board.

[1] When Western Samoa attained independence in 1962, the new constitution made Tupua Tamasese and Malietoa Tanumafili II (the two Fautua) joint heads of state.