Among the Ottoman posts he occupied were Governor of Crete 1895 and 1896, and ambassador in Saint Petersburg.

His governorship of Crete ended with the insurrection of May 24, 1896 that eventually led to the loss of the island by the Ottoman Empire.

Përmeti remained foreign minister until May 28, 1914, then replaced by Prenk Bib Doda, who himself was succeeded by Mehmed Konica in July.

[citation needed] Përmeti served as the second prime minister of Albania from 14 March 1914 to 3 September 1914 and on a second term from 25 December 1918 to 29 January 1920.

[6] Përmeti's government of the Principality of Albania (25 December 1918 – 29 January 1920) included Prenk Bib Doda, Mufid Libohova, Luigj Bumçi, Mustafa Merlika-Kruja, Mihal Turtulli, Mehmed Konica, Sami Vrioni, Mid'hat Frashëri, Luigj Gurakuqi, Lef Nosi, Fejzi Alizoti and also Petro Poga.