Tuscola is a city in Taylor County, Texas, United States.

According to the United States Census Bureau, the city has a total area of 0.7 square mile (1.9 km2), all land.

The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

[4] As of the 2020 United States census, there were 850 people, 305 households, and 203 families residing in the city.

23.8% of all households were made up of individuals, and 12.8% had someone living alone who was 65 years of age or older.