The two-story frame house was built in 1905 by contractor Benjamin Leon in the Colonial Revival style, an unusual choice for Nevada, and executed with particular opulence.

The entry porch features clusters of Ionic columns supporting a frieze and pediment.

Eaves are supported by brackets interspersed with decorative relief over the second floor windows.

[2] Eben Twaddle was a Reno-area rancher and was a six-term Reno city councilman, hospital administrator, school board representative and fire marshal.

[2] The Twaddle Mansion was listed on the National Register of Historic Places in 1983.