In the film's ending, Paul collapses while dancing, and the artist-physician goes to kiss him, their faces merging in superimposition.

[4][5] Markopoulos originally planned to include sync sound in Twice a Man but revised this several times while making the film.

[6][7] Markopoulos edited the scenes in order, with a highly intricate style in which shots may be broken up by sudden, rapid bursts of images.

Events at the house make reference to the offering of a lock of hair, the incestuous relation with Phaedra, and the heavenly rebirth.

[12] A silent version of Twice a Man screened at the Gramercy Arts Theatre on June 15, 1963, as part of a fundraiser organized by the Film-Makers' Cooperative to finish the film.

[14] Because of an incident at the festival where Flaming Creatures could not be screened, Mekas floated the idea of prize recipients refusing their awards; however, Markopoulos decided to accept it.