Twin Sisters is an unincorporated community in western Blanco County, Texas, United States.

A post office was established at Twin Sisters in 1856 and remained in operation until 1951 when it received its mail from Blanco.

He then opened a small brewery nearby, but it closed when he couldn't afford transportation and lacked cooling facilities.

His oldest son, Willy, then returned to the area and bought back the post office and general store and operated them until the 1940s.

[3] The climate in this area is characterized by hot, humid summers and generally mild to cool winters.