Twining Peak is set on the Continental Divide 2 miles (3.2 km) north of Independence Pass in the Sawatch Range which is a subrange of the Rocky Mountains.

[3] The mountain is located 15 miles (24 km) east of the community of Aspen on land managed by White River National Forest and San Isabel National Forest.

Topographic relief is significant as the summit rises 2,300 feet (701 m) above Roaring Fork River in one mile (1.6 km) and 2,500 feet (762 m) above North Fork Lake Creek in one mile (1.6 km).

[1] The mountain's toponym was officially adopted on January 1, 1974, by the United States Board on Geographic Names to honor Dr. Warren Hugh Twining (1876–1946), mayor of Aspen (1905–1907), member of Colorado House of Representatives (1925–34), and Speaker of the Colorado State House of Representatives (1933–34).

[5] Due to its altitude, it receives precipitation all year, as snow in winter, and as thunderstorms in summer, with a dry period in late spring.