The design process for her was more complicated than the others in Arms, as producer Kosuke Yabuki wished to consult Nintendo's American and European branches in an effort to represent people of different backgrounds and national origins.

She was first revealed in May 2017 Nintendo Direct, where she quickly became a fan favorite and a popular Black character in video games.

[14] Since her appearance in Arms, Twintelle has received generally positive reception, which made producer Yabuki happy, though he was surprised by how popular she became.

[17] Twintelle's popularity led to Nintendo including her in Arms' "Global Testpunch," a free temporary online video game demo.

[18] Critics, including Allegra Frank and Gita Jackson, suggested that her popularity was derived in part from her hair, outfit, attractiveness, and "calm, collected" personality.

[1][16] Writer Xavier Harding felt that the amount of fanart of Twintelle suggested that she would prove to be a popular Nintendo character.

Mic writer Tanya DePass was unhappy with Twintelle's design, criticizing the fact that she was a "brown, female character with weaponized hair."

She compared Twintelle to Black female athletes such as tennis player Serena Williams, who touched upon how she used to dislike her muscular body, but in time grew to love it due to how it has helped achieve her goals.

[27] Alisha Karabinus, Assistant Professor of Writing and Digital Studies at Grand Valley State University, acknowledged that Twintelle had potential problematic elements, but felt that they are not insurmountable issues, and said the key issue is a lack of representation and that there should be more playable Black female characters in video games.