"Two Times Blue" is a song by American singer Deborah Harry, released as the lead single from her fifth solo studio album, Necessary Evil (2007).

The pop rock song, produced by Super Buddha, finds Harry responding to a critical lover but confessing that she'd be unhappy if she left.

[7][8] In the verses, Harry responds to a lover who accuses her of being a "two timer" and "Miss Calculation", in turn defending herself and singing that she "can't give up—I love you through and through".

[3] The song's radio edit made more extensive use of synthesizers and deemphasize Harry's vocals; it's also longer than the original version, with a length of four minutes and twenty-nine seconds.

[11] An album review for Slant Magazine, penned by Sal Cinquemani, commended the song as the "epitome of geek-pop, even making algebra sound sexy".

[4] In January 2021, "Two Times Blue" was highlighted in a "Should Have Been Bigger" column for Idolator, with music journalist Mike Wass naming it one of Harry's "very best" releases and opining that it should have achieved a level of success comparable to that of Cher's "Believe.