In 1906, the Twohy family relocated to San Jose to construct the nearby Bayshore Cut-Off for Southern Pacific and supervise repairs to railroad bridges damaged by the San Francisco earthquake"[2][3] For example, it built part of the Southern Pacific Railroad.

[2] The building was designed by architect William Binder in the Classical Revival architectural style.

[1] It was built as a commercial building, with professional offices above a large ground floor drug store.

"Construction of the Twohy Building helped establish South 1st as the center of the business community in San Jose.

This article about a property in Santa Clara County, California on the National Register of Historic Places is a stub.