Txakoli de Álava (Basque) or Chacolí de Álava (Spanish) is a Spanish Denominación de Origen Protegida (DOP) (Basque: Jatorri Deitura Babestua) for wines, located around the towns of Amurrio, Llodio, Artziniega, Okondo and Aiara in the province of Álava, Basque Country, Spain.

Txacolí is a thin white acidic wine that can be naturally fizzy and is traditionally served like cider, poured from a height into the glass.

This DOP was created in 1989 on the initiative of the five remaining txacolí producers in the province.

However, wine had traditionally been made in this manner for hundreds of years and was popular from the Middle Ages up to the end of the 19th century, when the vines were devastated by the phylloxera and the effects of industrialization of the Basque Country.

The authorised grape varieties are: Almost all the vines are trained on trellises (en espaldera) due to the high levels of rainfall and humidity in the area.