Tyrone House in County Galway is a ruined manor house, built in the 1770s on a promontory by the estuary of the Kilcolgan river, about 2 miles (3 km) from the village of Kilcolgan, County Galway, Ireland.

[3] Writing in the 1780s, Daniel Augustus Beaufort described the house as '‘large and new but very bleak and too high'.

[4] Its original owner was Christopher St. George, scion of an old Norman Galwegian family.

It served as an inspiration for the novel "The Big House at Inver" by Edith Somerville, published in 1925.

[6] The house was destroyed by the local IRA unit during the Irish War of Independence in 1920[6] due to rumours that it was going to be used by the Black and Tans as an infirmary.