It is located in the western central part of the oblast.

The area of the district is 6,400 square kilometers (2,500 sq mi).

[7] Within the framework of administrative divisions, Tyukalinsky District is one of the thirty-two in the oblast.

[1] The town of Tyukalinsk serves as its administrative center, despite being incorporated separately as a town of oblast significance—an administrative unit with the status equal to that of the districts.

[1] As a municipal division, the district is incorporated as Tyukalinsky Municipal District, with the town of oblast significance of Tyukalinsk being incorporated within it as Tyukalinsk Urban Settlement.