Tyzenhauz Palace (Lithuanian Tyzenhauzų rūmai) is an 18th-century mansion located in the city of Vilnius, Lithuania.
Around 1765 the parcel was bought by Antoni Tyzenhauz (Antanas Tyzenhauzas in Lithuanian translation), a treasurer of Lithuania, starost of Grodno and a close friend of the Polish king Stanisław August Poniatowski.
A notable personality of the epoch, Tyzenhauz was a manager of royal grounds in the Grand Duchy of Lithuania and was responsible for a major industrialisation effort in the area of Grodno.
Later, after the city of Vilnius/Wilno became a part of Poland in 1922, the 2nd and 3rd floors were yet again reconstructed to house a Hotel Sokołowskiego, named after its owner.
This was due to the shortage of living space in Vilnius caused by a great deal of residential buildings having been destroyed.
After Lithuania regained her independence, the Vilnius Old Town became a prestigious place, and many of the occupants of the palace took the opportunity to sell their flats for a high price.
The attic was unused following the rebuilding after World War II, but has been put to commercial use since the collapse of the Soviet Union.