Built in 1932 and enlarged to include other federal offices in 1965, it is an architecturally distinguished building with Classical and Colonial Revival features.

[1] The main Sanford post office is located at the northeast corner of School and Mousam Streets, two blocks southeast of the city center.

A lower single-story addition is connected to the building at its eastern end, which has a separate entrance.

The main block is red brick, laid in Flemish bond, with granite and marble trim elements.

The design work was funded by a federal Depression-era program intended to provide employment for regional architects.