[1] The building, completed in 1896 in the Renaissance Revival style, was designed by Charleston architect John Henry Devereux using gray granite from Winnsboro, South Carolina.

The design includes a square tower, balustraded balconies, rusticated base and quoins, great double doors, and high and broad steps, meant to resemble an Italian Renaissance palace.

[4] The Charleston Post Office is one of the oldest in the United States, having been established by George III in 1740, during the provisional colonial governorship of William Bull.

In 1885, Devereux was appointed as Superintendent of Construction and Repairs of the U.S. Treasury Department, which then managed public buildings.

Completed for a cost of $500,000, the building is credited with playing an important role in the downtown revitalization of Charleston at the end of the 19th century.

Some of the hallmarks of the Renaissance Revival style found on the building include a prominent cornice, balustrades, and quoins (corner blocks).

The second story features rectangular window openings topped with prominent triangular pediments and flanked with pilasters (attached columns).

A prominent corner tower that ascends a full story above the rest of the building is located at the confluence of Meeting and Broad Streets.

Rich finishes include red Brazilian marble wainscot and floors, and mahogany walls at the sales and box areas.

A carved mahogany panel with floral and patriotic motifs, including a shield with stars and stripes, is located directly behind the judge's bench.

[4] In 1922, a modest, single-story, gray concrete addition for service functions was added to the south side of the building.