After starting its activity at youth levels, the team was granted the access to play the women's Eccellenza [it] (fourth tier of Italian women's football).

In their first season, Sampdoria were in the second position and lost the final of the promotion-play offs.

[7] Below is a list of Sampdoria Women coaches from 2020 until the present day.

Below is a list of Sampdoria Women presidents from 2020 until the present day.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.