Founded on 9 February 1923 and nicknamed Los Charros, the club played in white shirts and black shorts, holding home games at Estadio Helmántico, which seated 17,341 spectators.

On 16 March 1923, at the tables of Café Novelty, situated in the Plaza Mayor, Dionisio Ridruejo set the club's early official foundations[1][2] and, from 1939 and during the following three decades, it fluctuated between the third and the second levels of the Spanish football league.

In the 1974–75 season, Salamanca made its La Liga debuts, overachieving for a final 7th position (out of 18 teams), which eventually would be its best classification ever.

In 1994–95's second division, after finishing fourth in the league, Salamanca lost the first leg of the promotion/relegation playoffs against Albacete Balompié, 0–2 at home, but won 5–0 away, returning to the main level after eleven years.

[5] Numbers taken from the official website: www.udsalamanca.es and www.lfp.es Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.