UFC 285: Jones vs. Gane was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on March 4, 2023, at T-Mobile Arena in Paradise, Nevada, part of the Las Vegas metropolitan area, United States.

[3] Former champion Francis Ngannou was stripped of the title on January 14 and released from the promotion due to a contract dispute.

[8] They were previously scheduled to meet at UFC Fight Night: Dern vs. Yan but the bout was scrapped as Penne withdrew due to illness.

[10] They were previously expected to meet at UFC Fight Night: Strickland vs. Imavov but Neal withdrew due to injury.

[12] A middleweight bout between promotional newcomer Bo Nickal and Jamie Pickett took place at this event.