[2] In the main event, Anderson Silva put his UFC Middleweight Championship belt on the line against Nate Marquardt.

Post–fight, the California State Athletic Commission announced that both fighters tested positive for performance enhancing drugs.

Jason Gilliam was the third choice for Chris Lytle's opponent.

Originally scheduled to compete was Jeff Joslin, who withdrew due to a training injury.

The figures do not include any undisclosed bonuses:[1] Total disclosed payroll: $761,000[1]