A lightweight bout between Evan Dunham and Abel Trujillo was originally booked for UFC Fight Night: Poirier vs. Johnson.

[7] Subsequently, Andrade was removed from that card with the pairing left intact and rescheduled to take place at this event.

[8] On January 19, the card suffered multiple changes due to injury: Evan Dunham and Johnny Case pulled out of their respective fights against Abel Trujillo and James Vick.

[11] Jan Błachowicz was expected to face former interim UFC Light Heavyweight Championship challenger Ovince Saint Preux, but pulled out on January 21 due to injury and was replaced by promotional newcomer Volkan Oezdemir.

As a result, Rawlings was fined 20% of her purse, which went to Tecia Torres and the bout proceeded as scheduled at catchweight.

[18] On April 5, it was announced that Ledet accepted a four-month USADA's sanction for an anti-doping policy violation following an out-of-competition test conducted on January 12.