UFC Fight Night: Lewis vs. dos Santos (also known as UFC Fight Night 146 or UFC on ESPN+ 4) was a mixed martial arts event produced by the Ultimate Fighting Championship that was held on March 9, 2019 at Intrust Bank Arena in Wichita, Kansas.

[4] As a result of the cancellation of UFC 233, the women's bantamweight bout between former Invicta FC Bantamweight Champion and UFC Women's Featherweight Championship challenger Yana Kunitskaya and Marion Reneau was rescheduled for this event.

[5] Daniel Spitz was expected to fight Jeff Hughes at the event.

However, Spitz pulled out of the bout on February 16 citing injury and was replaced by Maurice Greene.

Hughes and Greene previously met in the regional circuit in April 2018.