The 2004–05 ULEB Cup was the third season of the second-tier level European professional club basketball competition, the EuroCup, which is organized by the Euroleague Basketball Company.

The season started on November 9, 2004, and officially ended on April 19, 2005.

Lietuvos rytas won the trophy, by defeating Makedonikos in the final, by a score of 78–74.

Top 2 teams from groups A, C, E, F, and G qualify to eighthfinals.

The winner of the two games with a higher combined score qualifies to quarterfinals.