On February 22, 2025, a mass shooting and hostage situation took place at UPMC Memorial Hospital in Shiloh, Pennsylvania, United States, near the city of York.

[2] The shooting began at around 10:35 a.m. when Diogenes Archangel-Ortiz took hostages at the intensive care unit (ICU) area of the hospital and opened fire on several people.

Later, when he came into the hallway with a female ICU employee at gunpoint with zip ties restraining her hands, both police officers and Archangel engaged in a shootout, in which he was fatally wounded.

[7] At least five people, including two police officers, a doctor, a nurse, and a custodian were wounded by gunshot but reported to be in stable condition.

Governor Josh Shapiro ordered national and state flags to be flown at half-mast across Pennsylvania in honor of Duarte.