[3][4] KH-11 satellites are used to provide high-resolution optical and infrared imagery for US intelligence agencies.

[7] After deploying its payload, the rocket's upper stage was deorbited after completing one orbit.

[2] The launch was the first Delta IV mission to use a new ignition sequence aimed at reducing damage to the first stage insulation caused by igniting a cloud of hydrogen around the vehicle at liftoff.

To mitigate this, the rocket's starboard engine was lit two seconds earlier than on previous flights.

[8] In 2020, MIT Technology Review reported that USA-245 was likely being "stalked" by a Russian satellite, Kosmos 2542, in a possible attempt to spy on US-245 to deduce its camera aperture and resolution, or its computer functionality and operating times.