USNS Spearhead (JHSV-1/T-EPF-1) is the lead ship of the Spearhead-class expeditionary fast transport to be operated by the United States Navy's Military Sealift Command.

Spearhead, and other ships of her class, are built to a modular design that allows them to be rapidly refitted with various equipment within a 20,000-square-foot (1,900 m2) bay, depending on the mission at hand.

[8] Spearhead, after delivery to the Navy in early 2012, will undergo sea trials and tests, and in the first quarter of fiscal year 2013 is planned to begin operations, homeported at Naval Amphibious Base Little Creek.

[9] She will be crewed by civilian mariners (merchant seaman) from the Military Sealift Command, and her first captain was Douglas D. Casavant Jr.[2] In August 2012 Spearhead made a "clean sweep" of her acceptance trials.

[16] From July to October 2018, Spearhead deployed to the Caribbean, South and Central America as part of the Navy's annual Southern Partnership Station (SPS) 2018.

[17] During the summer of 2019, Spearhead was part of a Navy project to test the EPF design as a drone mothership with various unmanned aerial vehicles (UAVs).